A Swiss Army Knife for Genomic Data
04-05-21
A good way to find out what a cell is doing—whether it is growing out of control as in cancers, or is under the control of an invading virus, or is simply going about the routine business of a healthy cell—is to look at its gene expression. Lior Pachter, Bren Professor of Computational Biology and Computing and Mathematical Sciences, has developed a complex software tool that enables the processing of large sets of genomic data in about 30 minutes, using the computing power of an average laptop. Like a Swiss Army knife, the tool can be used in myriad ways for different biological needs, and will help ensure the reproducibility of scientific studies. "The interdisciplinarity of our team was crucial to conceiving of and executing this project," says Pachter. "There are people in the lab who are computer scientists, biologists, engineers. Sina Booeshaghi is in the mechanical engineering department and brings the perspective of his design background and engineering." [Caltech story]
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CMS
Lior Pachter
Sina Booeshaghi
Lei Li Selected as 2021 TED Fellow
03-31-21
Lei Li, Postdoctoral Scholar Research Associate in Medical Engineering, has been selected as a 2021 TED Fellow. The TED Fellows program provides transformational support to a global community of over 500 remarkable individuals who are collaborating across disciplines to spark positive change around the world. Each TED Fellow was selected for their remarkable achievements, the potential impact of their work and their commitment to community building. [2021 Class of TED Fellows]
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Lei Li
Astronomers Image Magnetic Fields at the Edge of M87's Black Hole
03-24-21
The Event Horizon Telescope (EHT) collaboration, which produced the first-ever image of a black hole, revealed a new view of the massive object at the center of the M87 galaxy: a picture of its polarized light. This is the first time astronomers have been able to measure polarization, a signature of magnetic fields, this close to the edge of a black hole. "We are now able to see a different dimension of the light circling the M87 black hole," says Katie Bouman, Assistant Professor of Computing and Mathematical Sciences, Electrical Engineering and Astronomy, Rosenberg Scholar, and co-coordinator of the EHT Imaging Working Group. "The image we reconstructed earlier showed us how bright the light was around the black hole shadow. This image is telling us about the direction of that light." [Caltech story]
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CMS
Katie Bouman
Untangling the Heat Paradox Along Major Faults
03-12-21
Nadia Lapusta, Lawrence A. Hanson, Jr., Professor of Mechanical Engineering and Geophysics, and graduate student Valère Lambert, seek to explain the size of the forces acting on "mature faults"—long-lived faults along major plate boundaries like the San Andreas Fault in California—in an effort to better understand the physics that drive the major earthquakes that occur along them. Understanding the physics that govern major earthquakes on different types of faults will help generate more accurate forecasts for earthquake threats. "We have a lot of data from large earthquakes along subduction zones, but the last really major earthquakes along the San Andreas were the magnitude-7.9 Fort Tejon quake in 1857 and the magnitude-7.9 San Francisco Earthquake in 1906, both of them before the age of modern seismic networks," Lapusta says. [Nature article] [Caltech story]
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Nadia Lapusta
Valère Lambert
Professor Bouman Featured in Inverse Magazine
03-10-21
Katie Bouman, Assistant Professor of Computing and Mathematical Sciences, Electrical Engineering and Astronomy; Rosenberg Scholar, was featured in Inverse Magazine as one of the astronomers who captured the first image of a black hole. In 2019, Bouman and a group of more than 200 astronomers from all over the world managed the inconceivable: They captured the first image of a black hole, rendering the invisible visible. "Ideally, to see a black hole, we would need a telescope the size of the entire Earth," says Bouman. "We had to come up with a computational telescope that size." [Inverse article]
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CMS
Katie Bouman
Wei Gao Receives 3M Non-Tenured Faculty Award
03-08-21
Wei Gao, Assistant Professor of Medical Engineering, has been selected to receive the prestigious 3M Non-Tenured Faculty Award from 3M Corporation. This award recognizes outstanding new faculty who were nominated by 3M researchers and selected based on their research, experience and academic leadership. The purpose of the award is to help the faculty members achieve tenure, remain in their teaching position, and conduct research.
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Wei Gao
Professor Phillips Awarded Feynman Teaching Prize
03-01-21
The 2021 Richard P. Feynman Prize for Excellence in Teaching, Caltech's highest teaching prize, has been awarded to Rob Phillips, Fred and Nancy Morris Professor of Biophysics, Biology, and Physics. The Richard P. Feynman Prize for Excellence in Teaching was established in 1993 to honor annually a professor who demonstrates, in the broadest sense, unusual ability, creativity, and innovation in undergraduate and graduate classroom or laboratory teaching. "Being a professor at Caltech has been the signature privilege of my professional life," says Phillips. "Though I am deeply honored by this award, I am also totally cognizant of the generations of students that have joined me in my teaching and research adventures and without whom, none of this would have been possible. I have been surrounded by so many brilliant and dedicated young scientists that have joined me in celebrating the sense of wonder that fuels our science." [Past recipients] [Caltech story]
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Rob Phillips
Feynman Prize for Excellence in Teaching
