No Motor, No Battery, No Problem
05-15-18
Chiara Daraio, Professor of Mechanical Engineering and Applied Physics, and colleagues have developed robots capable of self-propulsion without using any motors, servos, or power supply. Instead, these first-of-their-kind devices paddle through water as the material they are constructed from deforms with temperature changes. "Combining simple motions together, we were able to embed programming into the material to carry out a sequence of complex behaviors," says Caltech postdoctoral scholar Osama R. Bilal, who is co-first author of the PNAS paper is titled "Harnessing bistability for directional propulsion of soft, untethered robots." [Caltech story]
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Chiara Daraio
MCE
APh
postdocs
Osama Bilal
Solving Pieces of the Genetic Puzzle
05-09-18
Postdoctoral scholar Nathan Belliveau working in the laboratory of Professor Rob Phillips has applied a method called Sort-Seq to mutate small pieces of noncoding regions in E. coli and determined which regions contain binding sites. Binding sites are the locations where specialized proteins that are involved in transcription—the first step in the process of gene expression—attach to DNA. "Humans have such a wide variety of cells—muscle cells, neurons, photoreceptors, blood cells, to name a few," says Professor Phillips. "They all have the same DNA, so how do they each turn out so differently? The answer lies in the fact that genes can be regulated—turned on or off, dialed up and dialed down—differently in different tissues. Until now, there have been no general principles to help us understand how this regulation was encoded." [Caltech story]
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Rob Phillips
APh
postdocs
Nathan Belliveau
Glowing Contact Lens Could Prevent A Leading Cause of Blindness
04-23-18
Hundreds of millions of people suffer from diabetes worldwide, putting them at risk for a creeping blindness, or diabetic retinopathy. Existing treatments, though effective, are painful and invasive, involving lasers and injections into the eyeball. Graduate student, Colin Cook working in Professor Yu-Chong Tai’s laboratory has invented a contact lens that when worn during sleep interrupts the process that destroys cells of the retina. He hopes his contact lenses will offer a solution that patients will be more willing to try because the effort involved is minimal, as are the side effects. [Caltech story]
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MedE
Yu-Chong Tai
Colin Cook
Caltech and Disney Engineers Collaborate on Robotics
01-18-18
Caltech and Disney Research have entered into a joint research agreement to pioneer robotic control systems and further explore artificial intelligence technologies. Pietro Perona will work with Disney roboticist Martin Buehler to create navigation and perception software that could allow robotic characters to safely move through dense crowds and interact with people. Aaron Ames will work with Disney Research's Lanny Smoot to further explore robot autonomy and machine learning by creating objects that can self-navigate and perform stunts. Yisong Yue has been working with engineers from Disney Research on the use of machine learning to analyze the behavior of soccer players and to measure audience engagement. [Caltech story]
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EE
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MCE
CMS
Pietro Perona
Yisong Yue
Aaron Ames
Building Blocks to Create Metamaterials
01-17-18
Chiara Daraio, Professor of Mechanical Engineering and Applied Physics, and colleagues have created a method to systematically design metamaterials using principles of quantum mechanics. "Before our work, there was no single, systematic way to design metamaterials that control mechanical waves for different applications," Professor Daraio says. "Instead, people often optimized a design to fulfill a specific purpose, or tried out new designs based on something they saw in nature, and then studied what properties would arise from repeated patterns." [Caltech story]
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Chiara Daraio
MCE
APh
Scientists Discover Unexpected Side Effect to Cleaning Up Urban Air
12-19-17
For decades, efforts to reduce air pollution have led to cleaner air in U.S cities like Los Angeles, with subsequent improvements in public health. Those efforts have targeted both nitric oxides and hydrocarbons. Hydrocarbons are emitted from many sources including gasoline-powered cars, trucks, solvents, cleaners used both at home and in industrial settings, and even trees. Professor Paul O. Wennberg and colleagues have found that there is another chemical pathway for forming organic hydroperoxides—one that occurs at nitric oxide levels substantially higher than can be found in the atmosphere over unpopulated regions. "This is chemistry that does not exist in any of the models of how nitric oxide and hydrocarbons interact," says Professor Wennberg. [Caltech story]
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ESE
Paul Wennberg
