News & Events


Professor Wang Advances Photoacoustic Imaging Technology


Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has developed variants of photoacoustic imaging that can show organs moving in real time, develop three-dimensional (3-D) images of internal body parts, and even differentiate cancerous cells from healthy cells. Photoacoustic imaging, a technique for examining living materials through the use of laser light and ultrasonic sound waves, has many potential applications in medicine because of its ability to show everything from organs to blood vessels to tumors. Wang has now further advanced photoacoustic imaging technology with what he calls Photoacoustic Topography Through an Ergodic Relay (PATER), which aims to simplify the equipment required for imaging of this type. [Caltech story]

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Ultrasound Can Selectively Kill Cancer Cells


Michael Ortiz, Frank and Ora Lee Marble Professor of Aeronautics and Mechanical Engineering, Emeritus, and Morteza Gharib, Hans W. Liepmann Professor of Aeronautics and Bioinspired Engineering; Booth-Kresa Leadership Chair, Center for Autonomous Systems and Technologies; Director, Graduate Aerospace Laboratories; Director, Center for Autonomous Systems and Technologies, are exploring a new technique that could offer a targeted approach to fighting cancer. Low-intensity pulses of ultrasound have been shown to selectively kill cancer cells while leaving normal cells unharmed. In the past, ultrasound waves have been used as a cancer treatment with high-intensity bursts resulting in killing cancer and normal cells. [Caltech story]

Tags: APhMS research highlights GALCIT MedE MCE Morteza Gharib Michael Ortiz

Professor Wang Develops World's Fastest Camera


Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has developed the world's fastest camera, a device capable of taking 10 trillion pictures per second. It's so fast that it can even capture light traveling in slow motion. "What we've done is to adapt standard phase-contrast microscopy so that it provides very fast imaging, which allows us to image ultrafast phenomena in transparent materials," says Wang. [Caltech story]

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Wearable Sweat Sensor Detects Gout-Causing Compounds


In a new paper published in Nature Biotechnology, Wei Gao, Assistant Professor of Medical Engineering, describes a mass-producible wearable sensor that can monitor levels of metabolites and nutrients in a person's blood by analyzing their sweat. Gao's sweat sensor is more sensitive than current devices and can detect sweat compounds of much lower concentrations, in addition to being easier to manufacture. "Considering that abnormal circulating nutrients and metabolites are related to a number of health conditions, the information collected from such wearable sensors will be invaluable for both research and medical treatment," Gao says. [Caltech story] [Read the paper]

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Professor Wei Gao Receives IEEE Sensors Council Award


Professor Wei Gao, Assistant Professor of Medical Engineering has received the 2019 IEEE Sensors Council Award for his "pioneering work on wearable and flexible chemical sensors toward continuous and personalized health monitoring." [List of award recipients]

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Professor Julia R. Greer Named Director of the Kavli Nanoscience Institute


Julia R. Greer, Ruben F. and Donna Mettler Professor of Materials Science, Mechanics and Medical Engineering, has been named the Fletcher Jones Foundation Director of the Kavli Nanoscience Institute (KNI). Greer replaces professors Oskar Painter and Nai-Chang Yeh, who served together as co-directors. "I am delighted to begin spearheading the wonderful enterprise of the KNI, humbly following the footsteps of my predecessors, professors Painter and Yeh. I have been a KNI member and on the board of directors since shortly after I arrived at Caltech," Greer says. [Caltech story]

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New Polymer Heart Valve Implanted in First Patient


Professor Morteza Gharib, has designed a new generation of heart valves that are longer-lasting, cost less to manufacture, and are more biocompatible than options that are currently available to patients. One of the new valves has been implanted into a human for the first time. "This is among my proudest moments. Creating something with the potential to save and improve lives is one of the reasons I became an engineer," Gharib says. [Caltech release]

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New Metamaterial Changes Shape in a Tunable Fashion


Julia R. Greer, Ruben F. and Donna Mettler Professor of Materials Science, Mechanics and Medical Engineering, has developed a new type of architected metamaterial that has the ability to change shape in a tunable fashion. The material has potential applications in next-generation energy storage and bio-implantable micro-devices. [Caltech story]

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A Promising Step in Returning Bipedal Mobility


Professors Aaron Ames and Joel Burdick have launched a new research initiative, RoAMS (Robotic Assisted Mobility Science), aimed at restoring natural and stable locomotion to individuals with walking deficiencies that result from spinal cord injuries and strokes. RoAMS unites robotic assistive devices—including exoskeletons and prostheses—with artificial intelligence (AI)-infused neurocontrol. "Bipedal walking is difficult to achieve in a stable fashion," says Professor Ames. "While crutches help users of the exoskeletons to stay upright, they undercut many of the health benefits that upright locomotion might otherwise provide. In addition, they do not allow users to do anything else with their hands while walking." [Caltech story]

Tags: research highlights MedE Yu-Chong Tai MCE CMS Joel Burdick Yisong Yue Aaron Ames

Microrobots Activated by Laser Pulses Show Promise For Treating Tumors


MedE Professors Wei Gao and Lihong Wang are working on microrobots that can deliver drugs to specific spots inside the body while being monitored and controlled from outside the body. "These micromotors can penetrate the mucus of the digestive tract and stay there for a long time. This improves medicine delivery," Professor Gao says. "But because they're made of magnesium, they're biocompatible and biodegradable." [Caltech story]

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