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Caltech and NTT Research Launch Collaboration to Develop World’s Fastest Coherent Ising Machine

01-25-21

Researchers from Caltech and NTT Research are collaborating to develop a high-speed Coherent Ising Machine (CIM). A CIM is a network of optical parametric oscillators (OPOs) programmed to solve problems that have been mapped to an Ising model, which is a mathematical abstraction of magnetic systems composed of competitively interacting spins, or angular momentums of fundamental particles. The principal investigator at Caltech for this four-and-a-half-year joint project is Kerry Vahala, Ted and Ginger Jenkins Professor of Information Science and Technology and Applied Physics; Executive Officer for Applied Physics and Materials Science. “We are delighted at the prospect of working with Professor Vahala to develop an extremely small and high-speed CIM,” said NTT Research PHI Lab Director, Yoshihisa Yamamoto. “This work will advance our understanding of the CIM’s capabilities, map well with ongoing and related work with other institutions, provide new demonstrations of this awesomely powerful new information system and, we hope, set standards for the CIM’s speed and size.” [NTT Research story] [Business Wire story]

Tags: APhMS research highlights Kerry Vahala KNI

Studying Chaos with One of the World's Fastest Cameras

01-14-21

There are things in life that can be predicted reasonably well. The tides rise and fall. A billiard ball bounces around a table according to orderly geometry. And then there are things that defy easy prediction: The hurricane that changes direction without warning. The splashing of water in a fountain. These phenomena and others like them can be described as chaotic systems. Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has developed a new tool that might help to better understand chaotic systems. [Caltech story]

Tags: EE research highlights MedE KNI Lihong Wang

Tiny Shape-Shifting Polymers Developed for Potential Medical Applications

01-04-21

Julia Greer, Ruben F. and Donna Mettler Professor of Materials Science, Mechanics and Medical Engineering; Fletcher Jones Foundation Director of the Kavli Nanoscience Institute, has developed a process for generating three-dimensional architected polymers with heat-dependent "shape memory" properties: that is, when heated, the material folds and unfolds itself into a new preordained shape. These shape memory polymers could one day be used to perform complex tasks inside the human body, such as unclogging a blocked artery or pulling out a blood clot. [Caltech story]

Tags: APhMS research highlights MedE Julia Greer KNI Luizetta Elliott

Lihong Wang Named to National Academy of Inventors

12-10-20

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has been named fellow of the National Academy of Inventors (NAI). Election as a fellow is the highest professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society. The Wang lab has developed photoacoustic imaging that allows researchers to see into biological tissues noninvasively, and to peer deeper into the body by nearly two orders of magnitude compared to conventional optical microscopy. [Caltech story] [List of 2020 Fellows]

Tags: EE honors MedE KNI Lihong Wang

Lihong Wang Receives NIH BRAIN Grant

12-07-20

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has received funding for neuroscience projects from the National Institutes of Health's Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Wang and his team aim to develop a technology called 3D photoacoustic computed tomography (PACT) that will rapidly image large-scale neural activity in human brains with high sensitivity. "Photoacoustic imaging of adult human brains is one of the most challenging frontiers in our field," says Wang. "It requires innovation to overcome the signal attenuation and wavefront distortion due to the skull. I'm glad that the NIH has the vision to fund this worthy research direction." [Caltech story]

Tags: EE research highlights MedE KNI Lihong Wang

Titanium Atom That Exists in Two Places at Once in Crystal to Blame for Unusual Phenomenon

12-07-20

Crystals are usually good at conducting heat. By definition, their atomic structure is highly organized, which allows atomic vibrations—heat—to flow through them as a wave. Austin Minnich, Professor of Mechanical Engineering and Applied Physics, has discovered why a perfect crystal is not good at conducting heat, although it seemingly should be. "We have found that quantum mechanical effects can play a huge role in setting the thermal transport properties of materials even under familiar conditions like room temperature," says Austin Minnich. [Caltech story]

Tags: APhMS research highlights MCE KNI Austin Minnich

Ultrafast Camera Films 3-D Movies at 100 Billion Frames Per Second

10-19-20

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has developed technology that can reach blistering speeds of 70 trillion frames per second, fast enough to see light travel. Just like the camera in your cell phone, though, it can only produce flat images. Now, Wang's lab has gone a step further to create a camera that not only records video at incredibly fast speeds but does so in three dimensions. [Caltech story]

Tags: EE research highlights MedE KNI Lihong Wang

A Method to Map Brain Circuits in Real Time

10-16-20

A new approach called integrated neurophotonics could allow researchers to track the activity of all the neurons that make up a particular brain circuit. To deepen their understanding of the brain, neuroscientists must be able to map in great detail the neural circuits that are responsible for tasks such as processing sensory information or forming new memories. Now, a new approach may allow for the activity of all of the thousands to millions of neurons within a particular brain circuit to be observed in real time. Dense recording at depth—that is the key," says Michael Roukes, Frank J. Roshek Professor of Physics, Applied Physics, and Bioengineering. [Caltech story]

Tags: APhMS research highlights Michael Roukes KNI

New Device Powers Wearable Sensors Through Human Motion

10-16-20

Wei Gao, Assistant Professor of Medical Engineering, has been developing sensors as well as novel approaches to power them. Previously, he created a sensor that could monitor health indicators in human sweat that is powered by sweat itself. Now, Gao has developed a new way to power wireless wearable sensors: He harvests kinetic energy that is produced by a person as they move around. "Instead of using fancy materials, we use commercially available flexible circuit boards," he says. "This material is cheap and very durable and mechanically robust over long periods of time." [Caltech story]

Tags: APhMS research highlights MedE KNI Wei Gao

Professor Gao Unveils Sensor that Rapidly Detects COVID-19 Infection Status, Severity, and Immunity

10-02-20

One feature of the COVID-19 virus that makes it so difficult to contain is that it can be easily spread to others by a person who has yet to show any signs of infection. Wei Gao, Assistant Professor of Medical Engineering, has developed a new type of multiplexed test (a test that combines multiple kinds of data) with a low-cost sensor that may enable the at-home diagnosis of a COVID infection through rapid analysis of small volumes of saliva or blood, without the involvement of a medical professional, in less than 10 minutes. "This is the only telemedicine platform I've seen that can give information about the infection in three types of data with a single sensor," Gao says. "In as little as a few minutes, we can simultaneously check these levels, so we get a full picture about the infection, including early infection, immunity, and severity." [Caltech story]

Tags: APhMS research highlights MedE KNI Wei Gao