Lihong Wang

Bren Professor of Medical Engineering and Electrical Engineering

Degrees and Appointments

B.S., Huazhong University of Science and Technology, 1984; M.S., 1987; Ph.D., Rice University, 1992. Visiting Associate, Caltech, 2016; Bren Professor, 2017-.

205 Keck MC 138-78 Pasadena, CA 91125


Terri Formico, Keck 207, 626-395-1970

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Research Overview

Professor Wang's laboratory reported the first functional photoacoustic tomography, 3D photoacoustic microscopy (PAM), optical-resolution PAM, photoacoustic Doppler effect, photoacoustic reporter gene imaging, microwave-induced thermoacoustic tomography, the universal photoacoustic reconstruction algorithm, frequency-swept ultrasound-modulated optical tomography, time-reversed ultrasonically encoded (TRUE) optical focusing, compressed ultrafast photography (capable of 100 billion frames per second), sonoluminescence tomography, Mueller-matrix optical coherence tomography, optical coherence computed tomography, and oblique-incidence reflectometry. Combining rich optical contrast and scalable ultrasonic resolution, photoacoustic imaging is the only modality capable of providing multiscale high-resolution structural, functional, metabolic, and molecular imaging of organelles, cells, tissues, and organs in vivo. In comparison to modern optical microscopy, photoacoustic imaging has advanced the penetration by nearly two orders of magnitude, breaking through the optical diffusion limit. His Monte Carlo model of photon transport in scattering media is used worldwide as a standard tool. 

List of Research Areas

Photoacoustic microscopy

Photoacoustic tomography

Wavefront engineering (wavefront shaping)

Compressed ultrafast photography

Ultrasound-modulated optical tomography


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Division of Engineering and Applied Science